Inherited Diseases Research Group Researchgroup

Almost every disease has genetic component. Although more than 10,000 monogenic diseases are known, and majority of them can be analyzed directly, the number of the newly identified monogenic disorders is growing every week. In addition to these diseases, many multifactorial disorders exist (AMI, VTE, asthma, AMD) with strong genetic component. In these cases, the genetic alteration does not directly disease-causing rather it contributes to the development of the disease. Based on both the literature and on our previous observations it is clear that the prevalence of many mutations is population-specific. The Inherited Disease Research Group investigates the molecular background of genetic diseases. It identifies and tests genetic alterations at molecular, biochemical and epidemiological levels. Given from the nature of these studies, all of its activities are done with close cooperation with clinicians.